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How to decompose hair follicle tissue to obtain suspension cells for hair growth?

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The pursuit of luscious locks has led scientists and researchers on a journey to explore innovative approaches to hair growth and regeneration. Among these, the combination of hair follicle cells and Platelet-Rich Plasma (PRP) has emerged as a promising avenue for stimulating hair growth. In this blog, we’ll delve into the fascinating world of hair follicle tissue decomposition, the extraction of suspension cells, and the potential effectiveness of pairing them with PRP.

In the field of hair growth, how to decompose hair follicle tissue to obtain suspension cells for hair growth? Hair follicle cells mixed with prp, how effective is it for hair growth?

Obtaining suspension cells from hair follicle tissue and utilizing them with Platelet-Rich Plasma (PRP) for hair growth is an area of ongoing research and experimentation. While I can provide you with some general information based on my last update in September 2021, please note that developments in this field may have occurred since then.

Isolation of Hair Follicle Cells: To obtain suspension cells from hair follicle tissue, researchers usually employ enzymatic and mechanical methods to dissociate the tissue into individual cells. Enzymes like trypsin and collagenase are often used to break down the extracellular matrix and separate the cells from one another. Mechanical disruption through cutting, mincing, or grinding can further help release cells from the tissue. This process yields a mixture of various cell types from the hair follicle, including dermal papilla cells, keratinocytes, and dermal sheath cells.

Platelet-Rich Plasma (PRP) and Hair Growth: PRP is a concentration of platelets derived from a person’s own blood, and it is rich in growth factors that can potentially stimulate cell activity, tissue repair, and regeneration. When used in the context of hair growth, PRP is often injected into the scalp to promote hair follicle health and encourage hair growth. The growth factors present in PRP can potentially enhance cell proliferation and angiogenesis (the formation of new blood vessels), which might aid in creating a favorable environment for hair follicles.

Effectiveness: The effectiveness of combining hair follicle cells with PRP for hair growth can vary from person to person. Some studies have reported positive results in terms of increased hair density and thickness when using PRP in combination with hair follicle cells. However, it’s important to note that the scientific consensus on the effectiveness of this approach is still evolving, and more rigorous research is needed to establish its true benefits.

Challenges and Considerations: There are several challenges and considerations associated with this approach:

  1. Cell Viability: Ensuring that the isolated hair follicle cells remain viable and functional after isolation is crucial for successful outcomes.
  2. Dosing and Administration: The optimal concentration of PRP, the frequency of injections, and the injection technique all need to be carefully determined.
  3. Patient Variability: Responses to PRP treatments can vary widely among individuals due to factors such as genetics, underlying health conditions, and the severity of hair loss.
  4. Scientific Evidence: While there is some evidence suggesting the potential benefits of PRP for hair growth, more controlled clinical trials with larger sample sizes are needed to establish its effectiveness conclusively.
  5. Long-Term Results: The longevity of the results achieved through this approach is still a subject of investigation. Maintenance treatments might be required to sustain the effects over time.


The fusion of hair follicle cells and PRP in the pursuit of hair growth is a captivating tale of science and rejuvenation. Although the journey is ongoing, the strides made in understanding the interplay between these elements hold promise for those seeking fuller and healthier hair. As the science evolves, the future of hair regeneration could well lie within the intricate dance of cells and growth factors.

It’s recommended that individuals interested in this approach consult with qualified medical professionals who specialize in hair restoration and regenerative medicine. They can provide personalized guidance based on the latest scientific knowledge and advancements in the field.

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